CHIROBIOTIC ® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Army Publishing Directorate Army Publishing DirectorateMissing: chirobiotic. Astec CHIROBIOTIC CSPs are based on 5, 10 or 16 μm, high-purity, porous silica gel. They differ in the nature of the bonded macrocyclic glycopeptide and resulting enantioselectivity. *Astec CHIROBIOTIC V and T differ from V2 and T2, respectively, in their bonding chemistry that gives them different selectivity and preparative capacity for certain.
complementary selectivity to the CHIROBIOTIC T and T2. The removal of the three carbohydrates has enhanced resolution for many of the amino acids, α -, β γ- and cyclic. It has shown. CHIROBIOTIC ® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. The CHIROBIOTIC™ T is based on bonding the amphoteric glycopeptide Teicoplanin to a 5µm silica gel through multiple covalent linkages. Teicoplanin contains 23 chiral centers surrounding four pockets or cavities. Hydrogen donor and acceptor sites are readily available close to seven aromatic rings.
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